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Medical Quizz

Pathophysiology and clinical medicine

1. Hepcidin, hemojuvelin and feroportin play a role in

in development of chronic diseases anemia
in pathogenesis of hemorrhagic complications in children suffering from hemophilia
in prevention of hemorrhagic complications in hemophilia
in the treatment of hemostatic disorders in children, with the effect of hepcidin as most prominent

2. Commonly, sideroachrestic anemia is not

accompanied by sideroblasts
a sign of myelodysplastic syndrome
caused by repeated loss of blood (e.g. in young women)
caused by vitamin B6 deficiency

3. Mechanism of action of diuretic furosemid consists in inhibiton of:

Sodium/Glucose membrane co-transport in proximal tubule
Sodium/potassium/chloride membrane co-transport
Urea reabsorption
Tubular secretion of urea

4. With sodium plasma concentration 140 mmol/l calculate how much sodium is filtered into primary urine in 24 hr; take sodium atomic mass rounded to 23 g/mol

32 g
64 g
100 g
0,5 kg

5. The most frequent implantation site in ectopic pregnancy is:

Cornual region of the uterus
Fimbriae of the Fallopian tube
Ampulla of the Fallopian tube
Abdominal cavity

6. Pre-esophageal dysphagia is accompanied by:

Heartburn
Epistaxis (bleeding from the nose)
Bleeding from the esophageal varices
Cough and recurrent pneumonias

7. Eponymic name for trisomy 13 is:

Down syndrome
Edwards syndrome
Patau syndrome
Klinefelter syndrome

8. Ivermectin is:

An antiparasitic drug
Dipeptidyl dipeptidase-IV inhibitor used to treat type 2 diabetes mellitus
A medicine used in the treatment of neonatal diarrhea
Well tolerated immunosupresiv used (a) in the treatment of rheumatoid arthritis and (b) in GVH reaction prevention after transplants

9. Sideroblasts

are a sign of disorder of iron incorporation into heme
are pathognomic for sideropenic anemia
are phagocyting cells in spleen (and liver), that take part in recycling of iron back to bone marrow by removing old and altered erythrocytes from the blood flow
jsou nezralé buňky červené řady typické pro hemochromatózu

10. Lipases by their nature belong to

esterases
proteases
protein kinases
glycerol kinases